Hybrid Course Drug Development and Advanced Technique for Drug Research

PROGRAM SCHEDULE: July 17-28, 2023
Time: 10.00 AM to 12:00 PM


Course Title:     Drug Development and Advanced Technique for Drug Research

Credit: One                                                           Instructor: Prof. Dr. M. Hafizur Rahman, Ph.D. (Japan)

CLASS SCHEDULE: JULY 17 to JULY 28, 2023                       Time: 10:00 AM to 12:00 PM)

Lecture No.DateTimeTopic
  1.  July 17, 2023  10:00-12:00 PM   Drug Design and Development: The Arts and ScienceBiotechnology and drug discovery: from bench to bedside
  2.  July 18, 2023  10:00-12:00 PM   Development of Animal Models for Drug Research  
  3.  July 19, 2023  10:00-12:00 PM   Translational of In-vitro Dosages to In-vivo for Drug Research
  4.  July 20, 2023  10:00-12:00 PM   Basic concepts of Pharmacokinetics  
  5.  July 21, 2023  10:00-12:00 PM   Basic concepts of Pharmacodynamics
6-8July 24- 26, 2023   Histological and Immunohistochemical (IHC) Techniques for Drug Research
  6  July 24, 2023  10:00-12:00 PM   The art and science of IHCTissue Harvesting and Fixation Tissue Processing, Tissue Sectioning, Slide preparationHematoxylin & Eosin (H&E) Staining.
  7  July 25, 2023  10:00-12:00 PM   Immunohistochemistry of rat/mice section. ImmunocytochemistryIHC uses and considerations
  8  July 26, 2023  10:00-12:00 PM   Antibodies and Antigens Selection of Primary and Secondary Antibodies for IHC Antibody Tittering, and Antigen unmasking for IHC Light & Fluorescent Microscopy, Magnification and Resolution, and Image processing.
9July 29, 202310:30 – 11:30 AMFinal Exam

CERTIFICATES: Registered participants will receive a digital certificate after the successful completion of all the necessary requirements of the course.

For more information: siren.lej@gmail.com;  Call:  021-111-222-292 Ext: 267, 275.

Room No. 202, 2nd floor, L.E.J. National Science Information Center, International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi-75270.

Final Exam:

Critical Success Factors (Passing Criteria)

Time duration of Exam: 60 minutes, Passing marks: Min 50 %,Attendance: >=75 % or as per
rules of ICCBS

Suggested reading

  1. Barrett JS (editor). Fundamentals of Drug Development. 1st ed. Wiley, USA: 2022.
  2. Drugs@FDA Glossary of Terms. US Food & Drug Administration; Silver Spring, MD, USA: 2022.
  3. Young DC (editor). Computational Drug Design. John Wiley & Sons, Inc.; Hoboken, NJ, USA: 2009.
  4. Rowland M and Tozer TN (editors). Clinical Pharmacokinetics and Pharmacodynamics. 4th ed. Lippincott Williams & Wilkins; Baltimore, MD, USA: 2011. Hafizur RM, Raza SA, Chishti S, Shaukat S and Ahmed A (2015) A ‘Humanized’ rat model of pre-diabetes by high fat diet-feeding to weaning Wistar rats. Integrative Obesity and Diabetes 1: 44-48
  5. Shaukat S and Hafizur RM (2014) A long term high fat diet/low dose streptozotocin develops a type 2 diabetic rat model showing clinical presentation and pathophysiology of natural history of diabetes. Journal of Biological and Chemical Research 31, 1187-1204.
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